Active Ingredient: Sodium Hyaluronate Intra-articular injection: Treatment of pain in osteoarthritis of the knee in patients who have failed nonpharmacologic treatment or simple analgesics (Euflexxa, Gel-One, Gelsyn-3, GenVisc 850, Hyalgan, Hymovis, Monovisc, OrthoVisc, Supartz, Supartz FX, Synvisc, Synvisc-One, Visco-3) or nonsteroidal anti-inflammatory drugs (NSAIDS) (Gel-One)
Intradermal:
Juvederm (all formulations except Volbella XC and Voluma XC), Perlane, Restylane, Restylane Defyne, Restylane Lyft, Restylane-L, Restylane Refyne: Correction of moderate to severe facial wrinkles or folds
Juvederm Volbella XC and Restylane Silk: Correction of perioral rhytids in adults >21 years.
Subcutaneous/supraperiosteal: Juvederm Voluma XC, Restylane Lyft: Correction of age-related volume deficit (deep [subcutaneous and/or supraperiosteal] injection) for cheek augmentation in the mid-face in adults >21 years
Ophthalmic: Surgical aid in cataract extraction (Amvisc, Amvisc Plus, Provisc); intraocular lens implantation (Amvisc, Amvisc Plus, Provisc); corneal transplant (Amvisc, Amvisc Plus); glaucoma filtration (Amvisc, Amvisc Plus); and retinal attachment surgery (Amvisc, Amvisc Plus)
Submucosal: Lip augmentation in adults >21 years (Restylane, Restylane-L, Restylane Silk, Juvederm Ultra XC, Juvederm Volbella XC)
Topical cream, gel: Management of skin ulcers and wounds