Active Ingredient: Azathioprine Renal transplantation: Adjunctive therapy in prevention of rejection of kidney transplants
Guideline recommendations: While azathioprine is FDA approved for adjunctive therapy in prevention of rejection after renal transplantation, it is no longer recommended as a first-line agent. The KDIGO clinical practice guidelines for care of kidney transplant recipients recommend a combination of maintenance immunosuppressive medications as maintenance therapy, including a calcineurin inhibitor and an antiproliferative agent (mycophenolate preferred) with or without corticosteroids. Azathioprine is recommended as a second-line antiproliferative agent for prevention of acute rejection
Rheumatoid arthritis: Treatment of active rheumatoid arthritis (RA), to reduce signs and symptoms